Hadgu raises concerns about how diagnostic tests for detecting Chlamydia trachomatis are evaluated and states that 'discrepant analysis strongly biases evaluations in favour of the new test'. He questions the sensitivity and specificity figures that are generated by discrepant analysis. It may be us
✦ LIBER ✦
Bias in the evaluation of DNA-amplification tests for detecting Chlamydia trachomatis by A. Hadgu, Statistics in Medicine, 16, 1391–1399 (1997)
✍ Scribed by Max Chernesky; John Sellors; James Mahony
- Publisher
- John Wiley and Sons
- Year
- 1998
- Tongue
- English
- Weight
- 58 KB
- Volume
- 17
- Category
- Article
- ISSN
- 0277-6715
No coin nor oath required. For personal study only.
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The purpose of this paper is to show that the sensitivity and specificity estimates obtained by 'discrepant analysis' are biased. Discrepant analysis is a widely used technique that attempts to provide estimates of sensitivity and specificity in the presence of an imperfect gold standard. Many resea