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Biallelic deletion 13q14.3 in patients with chronic lymphocytic leukemia: cytogenetic, FISH and clinical studies

✍ Scribed by Christian Chena; Julio Sánchez Avalos; Raimundo F. Bezares; Guillermo Arrossagaray; Karina Turdó; Alicia Bistmans; Irma Slavutsky

Book ID
114794417
Publisher
John Wiley and Sons
Year
2008
Tongue
English
Weight
100 KB
Volume
81
Category
Article
ISSN
0902-4441

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Deletions and translocations of 13q14 are the most frequent structural chromosome abnormalities found in chronic lymphocytic leukaemia (CLL). We have identified 13q14 translocations in the blood of 30 of 450 (6.6%) CLL patients by conventional cytogenetics, using tetradecanoyl phorbol 12-myristate 1