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bFGF expression mediated by a hypoxia-regulated adenoviral vector protects PC12 cell death induced by serum deprivation

โœ Scribed by Hou-Wen Hu; Xiao-Kun Li; Rong-Yuan Zheng; Jian Xiao; Jin-Qi Zeng; Sheng T. Hou


Book ID
116299241
Publisher
Elsevier Science
Year
2009
Tongue
English
Weight
613 KB
Volume
390
Category
Article
ISSN
0006-291X

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We used adenoviral-mediated gene transfer of human amyloid precursor proteins (h-APPs) to evaluate the role of various h-APPs in causing neuronal cell death. We were able to infect PC12 cells with very high efficiency because D90% of the cells were cytochemically positive for โค-galactosidase activit