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Beyond reuse in chiral immobilized catalysis: The bis(oxazoline) case

✍ Scribed by José M. Fraile; José I. García; C.I. Herrerías; José A. Mayoral; E. Pires; L. Salvatella


Book ID
104010169
Publisher
Elsevier Science
Year
2009
Tongue
English
Weight
765 KB
Volume
140
Category
Article
ISSN
0920-5861

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Bis(oxazoline) ligands have been used to prepare chiral catalysts for a large variety of enantioselective reactions. This versatility has attracted interest towards its immobilization, to profit from the advantages of using heterogeneous catalysis with respect to catalyst separation, possible recycl

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## Abstract __C__~2~‐Symmetrical boron complexes, prepared by the reactions of 2,2′‐methylenebis(oxazolines) (BOXs) with catecholborane (CATBH), can be used as catalysts (5–10 mol‐%) in the enantioselective reduction of prochiral ketones (__ee__ 72–86 %), giving the desired alcohols in satisfactory