✦ LIBER ✦

Beyond Picomolar Affinities: Quantitative Aspects of Noncovalent and Covalent Binding of Drugs to Proteins

✍ Scribed by Smith, Adam J. T.; Zhang, Xiyun; Leach, Andrew G.; Houk, K. N.

Book ID: 118739245
Publisher: American Chemical Society
Year: 2009
Tongue: English
Weight: 328 KB
Volume: 52
Category: Article
ISSN: 0022-2623
DOI: 10.1021/jm800498e

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

ChemInform Abstract: Beyond Picomolar Af

ChemInform Abstract: Beyond Picomolar Affinities: Quantitative Aspects of Noncovalent and Covalent Binding of Drugs to Proteins

✍ Adam J. T. Smith; Xiyun Zhang; Andrew G. Leach; K. N. Houk 📂 Article 📅 2009 🏛 John Wiley and Sons ⚖ 15 KB 👁 1 views

QUANTITATIVE AND QUALITATIVE ASPECTS OF

QUANTITATIVE AND QUALITATIVE ASPECTS OF THE PLASMA PROTEIN BINDING OF CARBENOXOLONE, AN ULCER-HEALING DRUG

✍ Dennis V. Parke; W. Edward Lindup 📂 Article 📅 1973 🏛 John Wiley and Sons 🌐 English ⚖ 730 KB

Methodological aspects of the evaluation

Methodological aspects of the evaluation of the binding of drugs to plasma and tissue proteins

✍ Jean -Paul Tillement; Edith Albengres; Saïk Urien 📂 Article 📅 1979 🏛 Springer-Verlag 🌐 English ⚖ 664 KB

CERTAIN ASPECTS OF DRUG BINDING TO NONPL

CERTAIN ASPECTS OF DRUG BINDING TO NONPLASMA PROTEINS AS ILLUSTRATED BY STUDIES WITH CYCLIZINE, CHLORCYCLIZINE, AND POLYMYXIN B

✍ R. Kuntzman; M. Jacobson; I. Tsai; J. J. Burns; J. Burchall; A. Koch 📂 Article 📅 1973 🏛 John Wiley and Sons 🌐 English ⚖ 693 KB

On the calculation of the concentration

On the calculation of the concentration dependence of drug binding to plasma proteins with multiple binding sites of different affinities: Determination of the possible variation of the unbound drug fraction and calculation of the number of binding sites of the protein

✍ Leonid M. Berezhkovskiy 📂 Article 📅 2007 🏛 John Wiley and Sons 🌐 English ⚖ 161 KB 👁 1 views

The measurement of the unbound drug fraction in plasma is routinely performed at drug concentrations much less than that of plasma proteins. Commonly, the protein has several binding sites of different affinities. The obtained value of the unbound drug fraction does not yield the affinity of each bi

Application of ion-pair methods to drug

Application of ion-pair methods to drug extraction from biological fluids II: Quantitative determination of biguanides in biological fluids and comparison of protein binding estimates

✍ Edward R. Garrett; Josef Tsau; Peter H. Hinderling 📂 Article 📅 1972 🏛 John Wiley and Sons 🌐 English ⚖ 1003 KB