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Beyond Epithelial to Mesenchymal Transition: A Novel Role for the Transcription Factor Snail in Inflammation and Wound Healing

✍ Scribed by Birgit Hotz; Alexander Visekruna; Heinz-Johannes Buhr; Hubert Georg Hotz


Book ID
107410838
Publisher
Springer-Verlag
Year
2009
Tongue
English
Weight
557 KB
Volume
14
Category
Article
ISSN
1091-255X

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## Abstract In the current study, we investigated the mechanism relating downregulation of mitogen‐activated protein kinase kinase 4 (MKK4) expression to development of ovarian cancer. Over‐expression of the MKK4 gene in TOV‐21 G cells, a line with homozygous deletion of MKK4, resulted in morpholog