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Beware Multiple Hypothesis Testing: The Curse of Type I Errors

โœ Scribed by D. Worthington


Book ID
125583765
Publisher
Palgrave Publishers Ltd.
Year
2006
Tongue
English
Weight
184 KB
Volume
57
Category
Article
ISSN
0160-5682

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โœ Janet Wittes; Oliver Schabenberger; David Zucker; Erica Brittain; Michael Prosch ๐Ÿ“‚ Article ๐Ÿ“… 1999 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 124 KB ๐Ÿ‘ 2 views

When sample size is recalculated using unblinded interim data, use of the usual t-test at the end of a study may lead to an elevated type I error rate. This paper describes a numerical quadrature investigation to calculate the true probability of rejection as a function of the time of the recalculat