✦ LIBER ✦
Betel nut-induced extrapyramidal syndrome: An unusual drug interaction
✍ Scribed by Martin Deahl
- Book ID
- 102506997
- Publisher
- John Wiley and Sons
- Year
- 1989
- Tongue
- English
- Weight
- 149 KB
- Volume
- 4
- Category
- Article
- ISSN
- 0885-3185
No coin nor oath required. For personal study only.
✦ Synopsis
Two cases are described of chronic schizophrenic patients maintained on depot neuroleptics, who developed severe extrapyramidal symptoms following a period of heavy betel nut consumption. A mechanism for this effect is proposed based on the pharmacological antagonism of the anticholinergic agent, procyclidine, by the active alkaloid ingredient of the betel, arecoline.