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Betaxolol hydrochloride: 1-{4-[2-(cyclopropylmethoxy)ethyl]phenoxy}-3-isopropylamino-2-propanol hydrochloride, C18H30NO3+.Cl−

✍ Scribed by Pascard, C. ;Tran Huu Dau, E. ;Manoury, P. ;Mompon, B.

Book ID
114502373
Publisher
International Union of Crystallography
Year
1984
Tongue
English
Weight
300 KB
Volume
40
Category
Article
ISSN
0108-2701

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Synthese du SL 75.212 (Betaxolol) Marque
Synthese du SL 75.212 (Betaxolol) Marque au Carbone 14 : [Cyclopropylmethoxy-2 Ethyl 14C-1)-4 Phenoxy] - 1 Isopropylamino-3 Propanol-2
✍ F. Aubert; J.-P. Beaucourt; L. Pichat 📂 Article 📅 1982 🏛 John Wiley and Sons 🌐 French ⚖ 364 KB

## Abstract The synthesis of SL‐75.212 (BETAXOLOL) labelled with carbon 14 : 1‐[4‐(2‐cyclopropyl methoxyethyl‐[1‐^14^C]) phenoxy]‐3‐isopropul amino‐2‐propanol : __13__ was achieved by a twelve step sequence from [^14^C] carbon dioxide. Carbonation with ^14^CO~2~ of the Grignard reagent __1__ gave