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Beta2-Adrenergic Receptor Polymorphisms Influence Response To Treatment In African-American Children With Near Fatal Asthma

✍ Scribed by Carroll, C.L.; Stoltz, P.; Schramm, C.M.; Zucker, A.R.


Book ID
119281412
Publisher
Elsevier Science
Year
2009
Tongue
English
Weight
40 KB
Volume
123
Category
Article
ISSN
1097-6825

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Influence of beta-2 adrenergic receptor
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The beta-2-adrenergic receptor (beta(2-)-AR) has several single-nucleotide polymorphisms. These influence the functional response to adrenergic stimulation; genotypes homozygous for Gly16-Glu27 or Gly16-Gln27 alleles (Gly16-Glu/Gln27 haplotypes) are associated with enhanced response, whereas genotyp