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Beta-catenin is not activated by downregulation of PTEN in osteoblasts

✍ Scribed by Emily Hays; Jaime Schmidt; Nalini Chandar

Book ID: 107427149
Publisher: Society for In Vitro Biology
Year: 2009
Tongue: English
Weight: 444 KB
Volume: 45
Category: Article
ISSN: 1475-2689
DOI: 10.1007/s11626-009-9189-2

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## Abstract Aberrant expression/localisation of β‐catenin has been implicated in the progression of oesophageal cancer. As a member of the Wnt‐signalling pathway, activated β‐catenin translocates into the nucleus and drives gene transcription. Insulin‐like growth factors (IGFs) have been implicated