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Beta-alanine protection against hypoxic liver injury in the rat

✍ Scribed by Mariapia Vairetti; Rita Carini; Maria Grazia De Cesaris; Roberta Splendore; Plinio Richelmi; Francantonio Bertè; Emanuele Albano

Book ID
117617888
Publisher
Elsevier Science
Year
2002
Tongue
English
Weight
438 KB
Volume
1587
Category
Article
ISSN
0925-4439

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## Abstract Mitochondrial respiration is inhibited in cells exposed to hypoxia, and the oxidation of NADH to NAD^+^ is blocked. As a result, oxidation reactions requiring NAD^+^ are blocked, disrupting cellular metabolism. We studied the influence of methylene blue, which oxidizes NADH, on hypoxic