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Benzyne cyclization route to benzo[c]phenanthridine alkaloids. Synthesis of chelerythrine, decarine, and nitidine

✍ Scribed by Kessar, Satinder V.; Gupta, Yash P.; Balakrishnan, Prasanna; Sawal, Kewal K.; Mohammad, Taj; Dutt, Mahesh


Book ID
120479206
Publisher
American Chemical Society
Year
1988
Tongue
English
Weight
771 KB
Volume
53
Category
Article
ISSN
0022-3263

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Transformation of protoberberines into b
✍ Miyoji Hanaoka; Hiroshi Yamagishi; Mari Marutani; Chisato Mukai πŸ“‚ Article πŸ“… 1984 πŸ› Elsevier Science 🌐 French βš– 259 KB

Antileukemic benzotclphenanthridine alkaloids, fagaronine (l(Y) and nitidine (1~) were synthesized from the corresponding protoberberines through C6-N bond fission and subsequent cyclization between C6 and Cl3 position of the protoberberines. Fully aromatized 2,3,8,9\_tetraoxygenated benzo[clphenant