The title compound were prepared aa useful optically active intermediates for the syntheals of "non-classical" B-lactam compounds. These monocyclic atetidinones were formed by cleavage of sulfur-carbon 5 bond of bicyclic penlcillanates with chlorine or tert-butyl hypochlorite in approplate solvents.
✦ LIBER ✦
Benzyl 2-[(2R,SS)-2-(benzylaminosulfinyl)-4-oxoazetidin-1-yl]-3-methylbut-2-enoate
✍ Scribed by Vinković, M. ;Herak, J. J. ;Kamenar, B.
- Book ID
- 114510222
- Publisher
- International Union of Crystallography
- Year
- 1993
- Tongue
- English
- Weight
- 309 KB
- Volume
- 49
- Category
- Article
- ISSN
- 0108-2701
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There are two molecules in the asymmetric unit of the title compound, C~28~H~24~N~2~O~4~S, an important intermediate in the synthesis of the cephem nucleus, which is convertible into broad-spectrum cephalosporin antibiotics. The two molecules have comparable conformations.