✦ LIBER ✦

Benzotriazol-1-ylmethyl isocyanide, a new synthon for CHNC transfer. Syntheses of α-hydroxyaldehydes, 4-ethoxy-2-oxazolines and oxazoles

✍ Scribed by Alan R. Katritzky; Ya-Xiong Chen; Konstantina Yannakopoulou; Ping Lue

Publisher: Elsevier Science
Year: 1989
Tongue: French
Weight: 269 KB
Volume: 30
Category: Article
ISSN: 0040-4039
DOI: 10.1016/s0040-4039(00)70643-5

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✦ Synopsis

Readily prepared benwtriazol-I-yEmethyl &cyanide (BetiUIC) reacts under mild conditions with ketones and ald&y&s, to afford oxazolines (convertible into a-hydroxyaldehydes,J and oxazoles, respectively.