Benzodiazepine inhibition of nucleoside transport in human erythrocytes
β Scribed by James R. Hammond; Simon M. Jarvis; Alan R.P. Paterson; Alexander S. Clanachan
- Book ID
- 115776924
- Publisher
- Elsevier Science
- Year
- 1983
- Tongue
- English
- Weight
- 756 KB
- Volume
- 32
- Category
- Article
- ISSN
- 0006-2952
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π SIMILAR VOLUMES
## Abstract The inhibition of glucose transport by the nonβionizable localβanesthetic benzylalcohol is of the mixed type and independent of pH. The affinity of benzylalcohol to the free carrier is about three times larger than that to the carrierβglucose complex.
Nucleoside transport in sheep erythrocytes is under the genetic control of two allelomorphic genes (NuI and Nui), where NuI codes for the functional absence of a high-affinity nucleoside transport system and is dominant to the gene (Nui) coding for the presence of the transport system. Kinetic and i