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Benzo[b]thiophene derivatives. XXV. Condensation and reductive alkylation of 3-aminoalkylbenzo[b]thiophenes with formaldehyde

✍ Scribed by E. Campaigne; E. Homfeld


Book ID
112125809
Publisher
Journal of Heterocyclic Chemistry
Year
1979
Tongue
English
Weight
299 KB
Volume
16
Category
Article
ISSN
0022-152X

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Reactions with benzo[b]thiophene-2,3-dio
✍ Mohamed Mohamed Mohamed Sallam; Mohamed Helmi Elnagdi; Mohamed Husein Abdel-Hady 📂 Article 📅 1975 🏛 John Wiley and Sons 🌐 German ⚖ 555 KB

## Abstract Benzo[b]thiophene‐2,3‐diones (**1**) react with __Grignard__ reagents to yield 2,3‐dihydroxy‐2,3‐diaryl(aralkyl)benzo[b]‐thiophenes (**2**). The latter compounds yield 3,3‐diaryl(aralkyl)‐benzo[b]thiophene‐2‐ones (**3**) by pinacolone rearrangement. Treatment of **3** by hot ethanolic s