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Benzo[a]pyrene-nucleic acid derivative found in vivo: structure of a benzo[a]pyrenetetrahydrodiol epoxide-guanosine adduct

✍ Scribed by Jeffrey, A. M.; Jennette, K. W.; Blobstein, S. H.; Weinstein, I. B.; Beland, F. A.; Harvey, R. G.; Kasai, H.; Miura, I.; Nakanishi, K.

Book ID
126999347
Publisher
American Chemical Society
Year
1976
Tongue
English
Weight
232 KB
Volume
98
Category
Article
ISSN
0002-7863

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In vivo formation of benzo (a) pyrene di
In vivo formation of benzo (a) pyrene diol epoxide-deoxyadenosine adducts in the skin of mice susceptible to benzo (a) pyrene-induced carcinogenesis
✍ Stephen W. Ashurst; Gerald M. Cohen 📂 Article 📅 1981 🏛 John Wiley and Sons 🌐 French ⚖ 824 KB

## Abstract The hydrocarbon‐deoxyribonucleoside adducts formed in mouse skin DNA have been determined following topical application of an initiating dose of benzo(a)pyrene to Swiss mice, a strain shown to be susceptible to benzo(a)pyrene‐induced skin carcinogenesis. Several DNA‐bound products were