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Benzo[a]pyrene Exposure Increases Toxic Biomarkers and Morphological Disorders in Mouse Cervix

✍ Scribed by Meili Gao; Yongfei Li; Ying Sun; Walayat Shah; Shuiyun Yang; Yili Wang; Jiangang Long


Book ID
111316995
Publisher
John Wiley and Sons
Year
2011
Tongue
English
Weight
564 KB
Volume
109
Category
Article
ISSN
1742-7835

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K-Ras mutant fraction (MF) was measured to examine the default assumption of low-dose linearity in the benzo[a]pyrene (B[a]P) mutational response. Groups of 10 male A/J mice (7- to 9-weeks old) received a single i.p. injection of 0, 0.05, 0.5, 5, or 50 mg/kg B[a]P and were sacrificed 28 days after t