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Benign familial neonatal-infantile seizures

✍ Scribed by Kaplan, Robert E. ;Lacey, Daniel J. ;Opitz, John M.


Publisher
John Wiley and Sons
Year
1983
Tongue
English
Weight
297 KB
Volume
16
Category
Article
ISSN
0148-7299

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Benign familial neonatal-infantile seizu
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## Abstract We recently reported mutations in the sodium channel gene __SCN2A__ in two families with benign familial neonatal‐infantile seizures (BFNISs). Here, we aimed to refine the molecular‐clinical correlation of __SCN2A__ mutations in early childhood epilepsies. __SCN2A__ was analyzed in 2 fa

Benign infantile familial convulsions ar
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Benign infantile familial convulsions (BIFC) and benign familial neonatal convulsions (BFNC) are two forms of familial convulsions having an age of onset within the first year of life. The gene responsible for BFNC has been mapped to chromosome 20q in the close vicinity of D20S19 and D20S20 markers.

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## Abstract Benign neonatal familial convulsions comprise a distinct epileptic syndrome with a autosomal mode of transmission. The electroclinical signs of seizures in this syndrome are not yet well defined. In 3 children from two families presenting with benign neonatal familial convulsions, 14 se