Beneficial hepatic effect of troglitazone in a patient with antimitochondrial antibody-negative primary biliary cirrhosis
β Scribed by Takashi Okai; Hisatsugu Mouri; Yasushi Yamaguchi; Yasuni Nakanuma; Norio Sawabu
- Book ID
- 119392047
- Publisher
- Nature Publishing Group
- Year
- 2002
- Tongue
- English
- Weight
- 40 KB
- Volume
- 97
- Category
- Article
- ISSN
- 0002-9270
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π SIMILAR VOLUMES
Primary biliary cirrhosis (PBC) is a chronic cholestatic liver disorder that can progress to cirrhosis, shortening life expectancy. PBC patients are often asymptomatic, present with biochemical cholestasis, and test positive (>90%) for antimitochondrial antibodies (AMAs) in serum. Although AMA posit
The presence of antimitochondrial antibodies (AMA) is a major criterion for the diagnosis of primary biliary cirrhosis (PBC). Although it is not clear that AMA are involved in the pathogenesis of the disease, the study of these autoantibodies has enabled much information to be accumulated about the