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Beneficial effects of silymarin on estrogen-induced cholestasis in the rat: A study in vivo and in isolated hepatocyte couplets

✍ Scribed by Fernando A. Crocenzi; Enrique J. Sánchez Pozzi; José M. Pellegrino; Cristin O. Favre; Emilio A. Rodrı́guez Garay; Aldo D. Mottino; Roger Coleman; Marcelo G. Roma


Book ID
111721578
Publisher
John Wiley and Sons
Year
2001
Tongue
English
Weight
296 KB
Volume
34
Category
Article
ISSN
0270-9139

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Tauroursodeoxycholate and S-adenosyl-L-m
✍ Piotr Milkiewicz; Charles O. Mills; Marcelo G. Roma; Jalal Ahmed-Choudhury; Elwy 📂 Article 📅 1999 🏛 John Wiley and Sons 🌐 English ⚖ 125 KB

The monohydroxy bile acid, taurolithocholate (TLC), causes cholestasis in vivo and in isolated perfused livers. It is also cholestatic in vitro and, in this study using isolated rat hepatocyte couplets, causes a reduction of the accumulation of (fluorescent) bile acid in the canalicular vacuoles (cV