✦ LIBER ✦

Beneficial effect of intranasal desmopressin for nocturnal polyuria in Parkinson's disease

✍ Scribed by Dr. Oksana Suchowersky; Sarah Furtado; Gina Rohs

Publisher: John Wiley and Sons
Year: 1995
Tongue: English
Weight: 362 KB
Volume: 10
Category: Article
ISSN: 0885-3185
DOI: 10.1002/mds.870100318

No coin nor oath required. For personal study only.

✦ Synopsis

Patients with Parkinson's disease (PD) are known to experience autonomic nervous system dysfunction; this disruptive symptomatology includes urinary urgency, frequency, and nocturnal polyuria. Anticholinergic and tricyclic medications can be beneficial in controlling these urinary symptoms, but have unpleasant side effects in some patients. Desmopressin has been used to treat nocturnal polyuria successfully in a number of conditions, such as central diabetes insipidus, enuresis, and autonomic failure. The purpose of the present study was to assess the efficacy of desmopressin in patients with PD with significant nocturia. Eight patients were recruited into the study.

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