𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Beiträge zum biologischen Abbau der Ölsäure

✍ Scribed by Karl Bernhard; Urs Gloor

Publisher
John Wiley and Sons
Year
1952
Tongue
German
Weight
651 KB
Volume
35
Category
Article
ISSN
0018-019X

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✦ Synopsis

Abstract

With the aid of the isotope‐dilution method we were able to show that both, man and dog, cannot oxidize oleic acid on the double bond with formation of azelaic acid. Healthy subjects excreted the deuterio azelaic acid with unchanged isotope concentration which would not be the case if this dicarboxylic acid was an intermediate product. Also oleyl alcohol, even as acetic acid—or benzoic acid ester, when fed to dogs, will not be metabolized to azelaic acid, but much easier oxidized to fatty acid.

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