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Behavioural Treatment of Lesch-Nyhan Syndrome

✍ Scribed by FRANCESCA LA VECCHIO; S. GILBERT M.Sc; E. SPELLACY MB.; R. W. E. WATTS M.D.

Book ID: 115263974
Publisher: John Wiley and Sons
Year: 2008
Tongue: English
Weight: 196 KB
Volume: 22
Category: Article
ISSN: 0012-1622
DOI: 10.1111/j.1469-8749.1980.tb03728.x

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Metabolic studies in a case of Lesch-Nyhan syndrome are presented. De novo synthesis of purine was shown to be inhibited upon adenine administration. The excretion of oxypurines is elevated, however, by an increased incorporation of the administered adenine into purine bases. A side effect of adenin