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Behavioural effects of naloxone in rats

✍ Scribed by A. Bertolini; S. Genedani; M. Castelli

Book ID
112658507
Publisher
Springer
Year
1978
Tongue
English
Weight
232 KB
Volume
34
Category
Article
ISSN
1420-682X

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Naloxone HCl (10 micrograms/0.5 ml) was injected in the locus coeruleus (LC) of morphine-dependent rats and the behavioural manifestations of morphine withdrawal and the cortical levels of 3-methoxy-4-hydroxyphenylethyleneglycol sulfate (MHPG-SO4) were measured 30 min later. Naloxone precipitated a