Behavioural and neurochemical abnormalities in mice lacking functional tachykinin-1 (NK1) receptors: A model of attention deficit hyperactivity disorder

Behavioural, pharmacological, morpho-fun

Behavioural, pharmacological, morpho-functional molecular studies reveal a hyperfunctioning mesocortical dopamine system in an animal model of attention deficit and hyperactivity disorder

✍ Davide Viggiano; Daniela Vallone; Lucia A Ruocco; Adolfo G Sadile 📂 Article 📅 2003 🏛 Elsevier Science 🌐 English ⚖ 125 KB

Clinical and experimental evidence suggest an involvement of dopamine systems, mainly the mesocorticolimbic one (MCL), in Attention-Deficit Hyperactivity Disorder (ADHD). However, it remains to be ascertained whether the systems are hyper-or hypo-functioning, for the implications of the functional s