Histopathological changes of rat brain a
β
Hiromi Sakai; Michiko Okamoto; Eiji Ikeda; Hirohisa Horinouchi; Koichi Kobayashi
π
Article
π
2009
π
John Wiley and Sons
π
English
β 756 KB
## Abstract For use as artificial oxygen carriers during transfusion, the safety and efficacy of Hbβvesicles (HbV, 250 nm), have been investigated extensively. Nevertheless, their neurotoxicity remains unknown. We explored potential adverse effects of HbV in the brain using a rat intracerebral hemo