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Behavioural and cognitive abnormalities in an imprinting centre deletion mouse model for Prader–Willi syndrome

✍ Scribed by Dinko Relkovic; Christine M. Doe; Trevor Humby; Karen A. Johnstone; James L. Resnick; Anthony J. Holland; Jim J. Hagan; Lawrence S. Wilkinson; Anthony R. Isles


Book ID
109028083
Publisher
John Wiley and Sons
Year
2010
Tongue
English
Weight
259 KB
Volume
31
Category
Article
ISSN
0953-816X

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## Abstract Prader–Willi syndrome (PWS) is caused by loss of paternally expressed genes in the 15q11‐q13 region. To further characterize alterations in gene expression in this classical obesity syndrome we used whole genome microarrays to study a PWS mouse model resulting from a paternally derived