Behavioural and biochemical effects of chronic treatment with amphetamine in the vervet monkey
β Scribed by R.M. Ridley; H.F. Baker; F. Owen; A.J. Cross; T.J. Crow
- Book ID
- 118954849
- Publisher
- Elsevier Science
- Year
- 1983
- Tongue
- English
- Weight
- 433 KB
- Volume
- 22
- Category
- Article
- ISSN
- 0028-3908
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w 18 x Ε½ . In six vervet monkeys, presynaptic striatal dopamine function was assessed longitudinally by F fluoro-L-DOPA FDOPA -positron Ε½ . Ε½ . Ε½ . emission tomography PET after administration 2 = 2 mgrkg, i.m., 4 h apart of either amphetamine Amp , n s 3, or metham-Ε½ . Ε½ . phetamine MeAmp , n s 3.
## Abstract Groups of male Wistar rats were injected with either apomorphine alone twice daily for one week or with apomorphine in combination with chlorpromazine or thioridazine. The neuroleptics were adminsitered once daily so that it was possible to assess their duration of effect on the apomorp