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Behavioural activity of (S)-3,5-DHPG, a selective agonist of group I metabotropic glutamate receptors

✍ Scribed by Alicja Zalewska-Wińska; Konstanty Wiśniewski


Book ID
118770858
Publisher
Elsevier Science
Year
2000
Tongue
English
Weight
173 KB
Volume
42
Category
Article
ISSN
1043-6618

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While it is well documented that the overactivation of ionotropic glutamate receptors leads to seizures and excitotoxic injury, little is known about the role of metabotropic glutamate receptors (mGluRs) in epileptogenesis and neuronal injury. Intracerebroventricular (i.c.v.) infusion of the group I