Behaviour of enaminomalonates and enamidomalonates under various reductive conditions: a novel synthetic approach to N-acetyl-N-aryl β-amino acids

✍ Scribed by Tomáš Solčan; Pavol Jakubec; Nadežda Prónayová; Viktor Milata

• Publisher: Elsevier Science
• Year: 2008
• Tongue: French
• Weight: 107 KB
• Volume: 49
• Category: Article
• ISSN: 0040-4039
• DOI: 10.1016/j.tetlet.2008.02.078

✦ Synopsis

The behaviour of enaminomalonates and their deprotection to amines under various reductive conditions is described. A new synthetic approach to N-aryl-N-acetyl-b-amino acids using heterogeneous catalytic hydrogenation has been discovered.