Behavioral “properties” of drugs
✍ Scribed by John R. Hughes; Stephen T. Higgins; Warren K. Bickel
- Publisher
- Springer
- Year
- 1988
- Tongue
- English
- Weight
- 123 KB
- Volume
- 96
- Category
- Article
- ISSN
- 0033-3158
No coin nor oath required. For personal study only.
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## Abstract The larval zebrafish has emerged as a vertebrate model system amenable to small molecule screens for probing diverse biological pathways. Two large‐scale small molecule screens examined the effects of thousands of drugs on larval zebrafish sleep/wake and photomotor response behaviors. B
Previous experiments (KELLY et al. 1958a, b; M~QvIS etal.; SMITiK et al.) have studied effects of meprobamate and other psychoactive drugs on the objectively measured behavior of normal subjects after acute and after chronic administration of the drug treatments. The present experiment investigates