Pharmacokinetic disposition of the novel
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Gregory M. Kochak; Ashok Rakhit; Frank Honc; C. James Mahoney
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Article
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1988
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Springer
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English
β 385 KB
The intravenous pharmacokinetic disposition of the novel, atypical anxiolytic CGS 9896 was studied in six cynomolgus monkeys. CGS 9896 was infused at dose levels of approximately 60, 120, and 240 ~tg/h/kg for a duration of 12 h, resulting in steady-state plasma concentrations averaging 38.4, 51.8, a