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Behavioral pharmacology of the pyrazoloquinoline CGS 9896, a novel putative anxiolytic

✍ Scribed by Sandra E. File; Sharon Pellow


Publisher
John Wiley and Sons
Year
1986
Tongue
English
Weight
552 KB
Volume
7
Category
Article
ISSN
0272-4391

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Pharmacokinetic disposition of the novel
✍ Gregory M. Kochak; Ashok Rakhit; Frank Honc; C. James Mahoney πŸ“‚ Article πŸ“… 1988 πŸ› Springer 🌐 English βš– 385 KB

The intravenous pharmacokinetic disposition of the novel, atypical anxiolytic CGS 9896 was studied in six cynomolgus monkeys. CGS 9896 was infused at dose levels of approximately 60, 120, and 240 ~tg/h/kg for a duration of 12 h, resulting in steady-state plasma concentrations averaging 38.4, 51.8, a