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Behavioral effects of dopamine agonists and antagonists in MPTP-lesioned D3 receptor knockout mice

✍ Scribed by Alex V Yarkov; Diane Hanger; Maria Reploge; Jeffrey N Joyce

Book ID
113840397
Publisher
Elsevier Science
Year
2003
Tongue
English
Weight
663 KB
Volume
76
Category
Article
ISSN
0091-3057

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✍ Michael P. Hill; Paula Ravenscroft; Steven G. McGuire; Jonathan M. Brotchie; Ala πŸ“‚ Article πŸ“… 2006 πŸ› John Wiley and Sons 🌐 English βš– 95 KB

L-dopa remains the most common treatment for Parkinson's disease. However, there is considerable interest in D3/D2 receptor agonists such as the novel agent S32504, since they exert antiparkinsonian properties in the absence of dyskinesia. An important question concerns the roles of D2 vs. D3 recept