Previous work in our laboratory has shown that the aziridinium ion of BM 123 (N-[4(2-chloroethylmethylamino)-2-butynyl]-2 pyrrolidone) is a potent and selective muscarinic agonist and binds irreversibly to muscarinic receptors (mAChR). The present series of experiments was designed to study the effe
Behavioral effects after intrathecal administration of cholinergic receptor agonists in the rat
β Scribed by P. G. Gillberg; P. Hartvig; T. Gordh; A. Sottile; I. Jansson; T. Archer; C. Post
- Publisher
- Springer
- Year
- 1990
- Tongue
- English
- Weight
- 850 KB
- Volume
- 100
- Category
- Article
- ISSN
- 0033-3158
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
Relatively high doses of systemically administered apomorphine inhibit penile reflexes. It is possible that these inhibitory effects are due, at least in part, to actions of apomorphine on the lumbosacral spinal cord. The present experiments examined this possibility by injecting apomorphine (10 and
Rats treated chronically with A 9-tetrahydrocannabinol (THC, daily oral dose 20 mg/kg) were examined for residual effects on a variety of behaviors following a 1-4month drug-free period. Learning a 12-arm radial maze and a differential reinforcement of low-rate responding (DRL-20) task was significa