Behavioral correlates of focal hippocampal x-irradiation in rats

✍ Scribed by R. B. Wallace; R. F. Kaplan; J. Werboff

• Book ID: 104675967
• Publisher: Springer-Verlag
• Year: 1976
• Tongue: English
• Weight: 645 KB
• Volume: 24
• Category: Article
• ISSN: 0014-4819
• DOI: 10.1007/bf00235002

✦ Synopsis

A study presenting findings of focal hippocampal x-irradiation in early infancy and late behavior at two ages was carried out using Long-Evans hooded rats (Rattus norvegicus). Animals from eleven litters received 150-R irradiation treatments for 5 or 15 consecutive days and were then tested in an open field situation and in a two-way active avoidance apparatus. The results indicated that the behavioral deficits paralleled those seen in animals with classical hippocampal lesions. The results were offered in support of a response suppression model for hippocampal functioning.