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Behavioral characterization of the 6-hydroxidopamine model of Parkinson’s disease and pharmacological rescuing of non-motor deficits

✍ Scribed by Miguel M Carvalho, Filipa L Campos, Bárbara Coimbra…

Book ID
120697191
Publisher
BioMed Central
Year
2013
Tongue
English
Weight
435 KB
Volume
8
Category
Article
ISSN
1750-1326

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## Abstract Investigation of the pathophysiology of psychosis in Parkinson's disease (PD), as well as the assessment of potential novel therapeutics, has been limited by the lack of a well‐validated animal model. MPTP‐lesioned primates exhibit abnormal behaviors that are distinct from dyskinesia an