Syntheses of (R,S)-naproxen and its 6-O-
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E. Fontana; S. Venegoni
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Article
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2008
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John Wiley and Sons
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French
β 87 KB
## Abstract Naproxen, a wellβknown nonβsteroidal antiβinflammatory drug, and its 6β__O__βdesmethylated metabolite have been labelled with ^2^H. (__R__,__S__)βNaproxen 7 labelled with ^2^H was obtained in five steps using the commercially available [^2^H~3~]iodomethane 5 as the stable labelled reage