Behavioral and neurochemical effects of repeated administration of Δ9-tetrahydrocannabinol in rats
✍ Scribed by C.S. Aulakh; A.K. Bhattacharyya; M.A. Hossain; S.N. Pradhan
- Book ID
- 118954256
- Publisher
- Elsevier Science
- Year
- 1980
- Tongue
- English
- Weight
- 601 KB
- Volume
- 19
- Category
- Article
- ISSN
- 0028-3908
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Rats treated chronically with A 9-tetrahydrocannabinol (THC, daily oral dose 20 mg/kg) were examined for residual effects on a variety of behaviors following a 1-4month drug-free period. Learning a 12-arm radial maze and a differential reinforcement of low-rate responding (DRL-20) task was significa
In an attempt to identify the possible role of brain biogenic amines and adrenocorticotrophic hormone (ACTH) release in the behavioral and physiological effects of A 9-tetrahydrocannabinol (THC), the time course of drug action was studied. THC (20 mg/kg) was administered daily for 1, 4, 21, or 42 da