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Behavioral and electrographic effects of opioids on kindled seizures in rats

โœ Scribed by S. Caldecott-Hazard; Y. Shavit; R.F. Ackermann; J. Engel Jr.; R.C.A. Frederickson; J.C. Liebeskind

Book ID
118867826
Publisher
Elsevier Science
Year
1982
Tongue
English
Weight
629 KB
Volume
251
Category
Article
ISSN
0006-8993

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Intraperitoneal phenytoin suppresses kin
Intraperitoneal phenytoin suppresses kindled responses: effects on motor and electrographic seizures
โœ E.W Lothman; J.M Williamson; K.E VanLandingham ๐Ÿ“‚ Article ๐Ÿ“… 1991 ๐Ÿ› Elsevier Science ๐ŸŒ English โš– 876 KB

Controversy has arisen about the effectiveness of phenytoin against kindled seizures. It has been suggested that the reports of ineffectiveness could be accounted for by phenytoin being given by an intraperitoneal (i.p.) route in those experiments so that adequate serum concentrations were not achie