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Behavioral and biochemical effects of subchronic treatment with (−)3-(3-hydroxyphenyl)-N-n-propylpiperidine in the rat: Dopamine receptor sensitivity and tolerance

✍ Scribed by S. Ahlenius; V. Hillegaart; O. Magnusson; J. Lundström


Publisher
Springer
Year
1984
Tongue
English
Weight
471 KB
Volume
60
Category
Article
ISSN
1435-1463

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## Abstract The motor effects of the partial dopamine agonist (–)‐3‐(3‐hydroxyphenyl)‐N‐n‐propylpiperidine [(–)‐3‐PPP, preclamol] were evaluated in nine patients with Parkinson's disease using a double‐blind, placebocontrolled design. (–)‐3‐PPP monotherapy had an antiparkinsonian effect in five of