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Behavior of 2-iminothiazolidin-4-one with different reagents

✍ Scribed by Wafaa S. Hamama; Mohadamed A. Ismail; Mamdoh Soliman; Saad Shaaban; Hanafi H. Zoorob


Publisher
Journal of Heterocyclic Chemistry
Year
2011
Tongue
English
Weight
184 KB
Volume
48
Category
Article
ISSN
0022-152X

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✦ Synopsis


Abstract

Annulations of 2‐imino‐4‐thiazolidinone (5) via cycloaddition followed by cyclocondensation reaction with 1,3‐diphenylpropenone (6), benzylidenemalonate, and 1,2‐bis(chloromethyl)benzene gave 7, 19 and 20, respectively. Reaction of 5 with suitable electrophiles (Mannich bases of arylalkanone), 1,4‐dichlorobenzene (diarylmethylation), and formylation afforded 8/9, 21/22, and 23, respectively. J. Heterocyclic Chem., (2011).


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