Begacestat (GSI-953): A Novel, Selective Thiophene Sulfonamide Inhibitor of Amyloid Precursor Protein -Secretase for the Treatment of Alzheimer's Disease

✍ Scribed by Martone, R. L.; Zhou, H.; Atchison, K.; Comery, T.; Xu, J. Z.; Huang, X.; Gong, X.; Jin, M.; Kreft, A.; Harrison, B.; Mayer, S. C.; Aschmies, S.; Gonzales, C.; Zaleska, M. M.; Riddell, D. R.; Wagner, E.; Lu, P.; Sun, S.-C.; Sonnenberg-Reines, J.; Oganesian, A.; Adkins, K.; Leach, M. W.; Clarke, D. W.; Huryn, D.; Abou-Gharbia, M.; Magolda, R.; Bard, J.; Frick, G.; Raje, S.; Forlow, S. B.; Balliet, C.; Burczynski, M. E.; Reinhart, P. H.; Wan, H. I.; Pangalos, M. N.; Jacobsen, J. S.

• Book ID: 118123861
• Publisher: American Society for Pharmacology and Experimental Therapeutics
• Year: 2009
• Tongue: English
• Weight: 400 KB
• Volume: 331
• Category: Article
• ISSN: 0022-3565
• DOI: 10.1124/jpet.109.152975