A variety of ketoximes undergo the Beckmann rearrangement when heated with 0.5 molar equiv. of chloral (neat melt/ 130Β°C), to furnish the corresponding amides in excellent yields (generally 80-95%) after simple work-up. (Aromatic aldoximes dehydrated to the corresponding nitriles in excellent yields
β¦ LIBER β¦
Beckmann Reaction of Oximes Catalyzed by Chloral: Mild and Neutral Procedures.
β Scribed by Sosale Chandrasekhar; Kovuru Gopalaiah
- Publisher
- John Wiley and Sons
- Year
- 2003
- Weight
- 110 KB
- Volume
- 34
- Category
- Article
- ISSN
- 0931-7597
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