Beckman cleavage of 1,2,3,4,5,6-hexahydro-3,6-dimethyl-2,6-methano-3-benzazocin-11-one oxime (2,5-dimethyl-9-oxo-6,7-benzomorphan oxime); a new route to 3-benzazocines
β Scribed by Brian Iddon; Donald Price; Hans Suschitzky; David I.C. Scopes
- Publisher
- Elsevier Science
- Year
- 1983
- Tongue
- French
- Weight
- 236 KB
- Volume
- 24
- Category
- Article
- ISSN
- 0040-4039
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β¦ Synopsis
The title reaction gave 1,2,3,4-tetrahydro-3,6-dimethyl-3benzazocine-2-carbonitrile 18) which showed some expected and some unexpected properties.
π SIMILAR VOLUMES
The nitrosation of some y,&unsaturated B-diketo compounds affords the 3-substituted 4-oxo-5,6-dihydro-1,2,4ff-oxaxines. These compounds are converted to the isomeric 3-oxo-1-pyrroline l-oxides by a facile thermal rearrangement. In connection with our study of y,s-unsaturated 6-ketoesters1'2, we have
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