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BCR-ABL1 tyrosine kinase sustained MECOM expression in chronic myeloid leukaemia

✍ Scribed by Swagata Roy; Heather G. Jørgensen; Poornima Roy; Mohamed Abed El Baky; Junia V. Melo; Gordon Strathdee; Tessa L. Holyoake; Chris Bartholomew


Book ID
114714659
Publisher
John Wiley and Sons
Year
2012
Tongue
English
Weight
406 KB
Volume
157
Category
Article
ISSN
0007-1048

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## Abstract We analysed the dynamic change of imatinib‐resistant mutations in BCR‐ABL kinase domain focusing on T315I mutation during dasatinib or nilotinib therapy. Fifty‐five imatinib‐resistant chronic myeloid leukaemia patients (32 patients with imatinib‐resistant mutations and 23 patients witho