Regulation of apoptosis in fibroblast-li
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Wafa Kammouni; Keng Wong; Guoping Ma; Gary S. Firestein; Spencer B. Gibson; Hani
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Article
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2007
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John Wiley and Sons
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English
β 212 KB
π 2 views
## Abstract ## Objective Rheumatoid arthritis (RA) synovial hyperplasia is related in part to a resistance to apoptosis exhibited by fibroblastβlike synoviocytes (FLS). Since hypoxia is a regulator of apoptosis, and since RA synovium is hypoxic, we conducted this study to examine the effects of hy