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BCL-2 transgenic mice are resistant to ischemia/reperfusion injury of the liver

✍ Scribed by Hannes A. Rudiger; David Sindrum; Pierre-Alain Clavien

Book ID: 119526860
Publisher: Elsevier Science
Year: 2001
Tongue: English
Weight: 311 KB
Volume: 34
Category: Article
ISSN: 0168-8278
DOI: 10.1016/s0168-8278(01)80905-3

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## Background: Apoptosis has been shown to contribute to myocardial reperfusion injury. it has been suggested that, in reducing the apoptotic component within the ischemic area at risk, bcl-2 overexpression could lead to a ventricular function improvement. ## Methods: Transgenic mice overexpressi