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Bcl-2 overexpression inhibits TRAIL-induced apoptosis in type II cells


Book ID
117659895
Publisher
Elsevier Science
Year
2002
Tongue
English
Weight
165 KB
Volume
38
Category
Article
ISSN
0959-8049

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## Abstract TCHQ is a major carcinogenic metabolite of the widely used wood preservative PCP. Recently, we found that TCHQ was a promoter in a mouse skin carcinogenesis model. However, the mechanism is still not clear. In this study, we showed that overexpression of Bclโ€2 effectively suppressed TCH